MeKo-Lab

• More than 120 stereo microscopes (Olympus, Zeiss, Leica, Vision Engineering)
• More than 100 special high-end inspection microscopes
  • measurements with an accuracy of 1 µm
• Stent scanners developed in-house
• Automated measuring systems
• Confocal laser scanning microscope
• Tensile testing
• Radial strength testing of stents
• Cross section and grain analysis
• Surface roughness
• Scanning Electron Microscopes (SEM)
• Energy Dispersive X-ray Spectroscopy (EDS) surface analysis
• Bend and Free Recovery (BFR)
• Differential Scanning Calorimeter (DSC)
• Electrochemical Impedance Spectroscopy (EIS)
• Potentiodynamic tests
• Degradation Test Lab (DTM)
• Atomic Force Microscope (AFM)
• ...

Special trained inspectors operate the instruments. MeKo provides ergonomic work places to improve inspectors’ concentration.

Through the use of automatic microscopes hundreds of measurements can be taken on a single work piece.

The results of these measurements ensure our customers the highest level of measurement confidence possible.

The Bend and Free Recovery (BFR) method is applied for measuring the active Af temperature of NiTi devices.

• Accurate method for all geometries → no limitations for sensitive parts
• Self-developed in-house and optimized for accurate measurements
• Non-destructive method for verifying the real transformation behavior
• Computer-assisted, fully automatic temperature cycling
• Printed graph including the Af temperature determined

Please see also DSC below

We take cross sections of devices to analyze grain structures, heat affected zones of laser welds, ...

MeKo performs in-vitro degradation tests for magnesium scaffolds:

• simulated blood circulation
• controlled flow rate, pressure, pulsation and temperature of circulation
• blood substitute solution for standardized tests: PBS, SBF, ...
• accelerated in-vitro degradation tests
  •    fast and reproducible evaluation of degradation
  •    monitoring and visualization of degradation process
  •    prediction of in-vivo degradation behavior

Informations about bioresorbable implants

Utilizing DSC, MeKo determines the transformation temperatures (Af temperatures) of shape memory alloys like NiTi (Nitinol).

• Precise measurement of the transformation temperatures by use of representative samples.
• Results can be linked to BFR (Bend and Free Recovery) measurements.
• A DSC graph - including the evaluation of the Af temperature of the heat treated parts will be sent along with the medical devices.

With our EDS system, material compositions and surface contaminations are analyzed.

The EIS is typically applied to measure the AC-current and AC potential.

In corrosion testing, EIS is standard practice for measuring the polarization resistance (Rp) of corroding systems.

Using Scanning Electron Microscopes (SEM), MeKo investigates devices with high resolution and a magnification up to 30,000x.

With potentiodynamic measurements the passivation and corrosion resistance of products are analysed in accordance with ASTM F2129.

At MeKo we measure the surface roughness in accordance with DIN EN 4758.

At MeKo, we know how to change the mechanical properties of implant materials by means of heat treatment.

To document the results, MeKo does not only check the time-temperature-curves of each heat treatment but also verifies the results by tensile tests.